A major focus of the project

Longevity

AI and the science of living longer.

Scientists are now using AI to search for treatments that slow aging. Drug companies and investors are paying attention, and the news is moving fast. Here’s what’s real, what’s hype, and what it could mean for all of us.

The question in our title

What if you live?

What if you, your children, or your grandchildren live much longer, healthier lives than anyone before? It’s the question at the heart of this project. This page follows the science as it happens.

Why now

Four signs that longevity is becoming a big AI story

Updated October 2026. We explain each story in plain words, with the fine print included.

Drug companies

Big drug companies are joining the conversation.

At ARDD 2026, a major aging-research meeting held at Harvard on October 1–3, the program included leaders from Novartis, Pfizer, Eli Lilly, Novo Nordisk, AstraZeneca and other large drug makers.

Keep in mind: A few years ago, aging research was mostly in university labs and small startups. Now the biggest companies in medicine are at the table.

Source: ARDD 2026 announcement (Insilico Medicine)

AI-designed drug

A drug found with AI, measured with “aging clocks.”

Rentosertib is a drug for lung scarring that was discovered with the help of AI. In a small study of 42 patients published in September 2026, four “aging clocks” (blood tests that estimate how old your body seems) read about three years younger on average after four weeks.

Keep in mind: The researchers say this does not show patients actually got younger or will live longer. The study was small, and the drug may simply have been helping the lungs.

Source: Lifespan.io, Sept. 11, 2026

AI as a researcher

An AI that reads the research for us.

A team led by Vadim Gladyshev built an AI system, ClockBase Agent, that combed through more than 43,000 past experiments, using over two million samples, looking for anything that seemed to slow aging. One drug it flagged, ouabain, an old heart medicine, made older mice healthier in follow-up tests.

Keep in mind: It’s a promising way to search, but the result is in mice, not people, the study hasn’t been peer reviewed yet, and the AI made some reasoning mistakes along the way.

Source: Lifespan.io, Nov. 27, 2025

Big money

Billions of dollars are betting on longer lives.

In June 2026, NewLimit, a company working to reprogram aging cells, raised $435 million to start its first clinical trial. OpenAI also built a special AI model with Retro Biosciences to redesign proteins used to make old cells act young again.

Keep in mind: Money isn’t proof. The OpenAI and Retro lab results are the companies’ own reports and haven’t been independently confirmed.

Source: STAT, June 2, 2026 · OpenAI

Real or hype?

Sorting the claims honestly

The same way our Realities of Our Evolution series does: by how sure we can be.

Certainties

What’s already true

  • Exercise, sleep, good food, friendships and not smoking add healthy years. This is still the strongest evidence we have.
  • AI is already helping scientists find and test new drug ideas faster.
  • People in most countries live far longer than they did 150 years ago.

Probabilities

What’s likely

  • More AI-discovered drugs for diseases of aging, such as heart disease and lung disease, reaching patients.
  • Better “aging clocks” that help doctors and researchers measure whether a treatment works.
  • Big debates about cost and who gets access first.

Possibilities

What could happen

  • Treatments that slow or partly reverse aging in people, not just in mice.
  • “Longevity escape velocity”: medicine adding years faster than we age.
  • Healthy lifespans well past 100.
Can medicine outrun aging?Our free Longevity Escape Velocity guide explains the idea in plain words, and what is still argued.Read the guide

The human questions

What it means for all of us

Living longer isn’t just a science story. These are the questions the project exists to talk about.

01

Who gets it first?

If new treatments are expensive, could the rich live decades longer than everyone else? How do we make sure no one is left behind?

02

Work and retirement

If 80 becomes the new 60, what happens to careers, retirement age, pensions and Social Security?

03

Families and generations

What changes when five generations are alive at once, and grandparents stay healthy for decades longer?

04

A crowded planet?

Would longer lives mean more people, more strain on resources, or simply smaller, older societies?

05

Meaning and purpose

If you had thirty more healthy years, what would you do with them? What makes a long life a good one?

06

Who decides?

Regulators don’t yet treat aging itself as something a drug can be approved to treat. Should that change, and who should decide?

Start here

Learn more, at your own pace

Free guide

Longevity Escape Velocity

Can medicine outrun aging? What the science shows and what’s still argued, in plain words.

Start reading →

Book

What if You Live?

The book behind the project: how AI will touch every part of society, and how no one gets left behind.

Get the book →

Lessons

AI Basics: twelve lessons

New to AI? Start here, so the longevity news makes more sense.

Begin Lesson 1 →

Talk about it

Join the longevity conversation

Would you want to live to 120? Who should get these treatments first? Share your thoughts in our free forum. Anyone can read; posting takes a free account.

This page is for general education, not medical advice. Talk with your doctor before changing medicines, supplements or your health routine.